Clinical Biochemistry Book | Prometric Exam – 2025

PROMETRIC EXAM MCQ MATERIAL FOR DHA -MOH -HAAD (DoH) -DHCC -SMLE – SCHFS– OMSB – QCHP – NHRA – KMLE

Clinical Biochemistry Prometric Exam MCQ

Product Details – 2025 Edition

Hard Copy Book

• Paperback: 702 pages
• Total Questions: 2000
• Practice Tests: 8
• Printing: Black and White
• Product Weight: 2 KG
• Product Dimensions: 8.5 x 2.1 x 11.5 inches

Online Subscription (Instant Access)

• Price: 69$
• Total Questions: 2000
• Practice Tests: 9
• Validity: 8 Months from the date of purchase

• Explanations: Detailed Explanations for effective learning
• Update Frequency: Every Year
• Success Rate: Over 80%
• Source: Previous exams and, All topic wise questions
• Topics: For all Prometric Exams in Gulf Countries
• Recommendation: Most recommended book for all Prometric Exam
• Language: English
• Publisher: Medical Exam Books – Rapid Access Guide Publishers™
• ISBN: 978-81-958196-4-6

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Best Clinical Biochemistry Prometric Exam Questions 2025

1) Cystinuria and Methionine Restriction

Question:
An 18-year-old boy was brought to the hospital by his mother due to a sudden onset of flank pain in his left side, radiating toward his pubic area. His urine was reddish-brown in color, and a urinalysis showed the presence of many red blood cells. When his urine was acidified with acetic acid, clusters of flat, hexagonal transparent crystals were noted. A radiograph of the abdomen showed radio-opaque stones in both kidneys. The boy eventually passed a stone whose major component was identified as cystine.
A suggestion for treatment is which of the following?

A. Increased ethanol consumption
B. Restriction of dietary methionine
C. Utilize drugs that acidify the urine
D. Restrict dietary glycine

✅ Correct Answer: B. Restriction of dietary methionine

Explanation:
The boy has cystinuria, caused by a defect in a kidney transporter that reabsorbs cystine. This leads to high cystine concentration in urine, causing stone formation.
Cysteine is derived from methionine, so reducing methionine lowers cysteine and cystine levels.
Ethanol or urine acidification increases stone risk, while glycine restriction is ineffective.

2) Cirrhosis and Ascites Formation

Question:
A 75-year-old chronic alcoholic man presents with a distended abdomen consistent with ascites. Which of the following liver functions has been compromised to cause this finding?

A. Lipid metabolism
B. Albumin synthesis
C. Estrogen metabolism
D. Alcohol detoxification

✅ Correct Answer: B. Albumin synthesis

Explanation:
Cirrhosis leads to decreased albumin synthesis, lowering oncotic pressure and causing ascites. Albumin maintains plasma oncotic pressure. Lipid metabolism, estrogen metabolism, or alcohol detoxification are not directly responsible for ascites.

3) Primaquine and Enzyme Deficiency Screening

Question:
Before prescribing primaquine to a male patient of African descent visiting a malaria-endemic region, which nonsymptomatic enzymatic deficiency should be tested?

A. Transketolase
B. Pyruvate dehydrogenase
C. α-Ketoglutarate dehydrogenase
D. Glucose-6-phosphate dehydrogenase

✅ Correct Answer: D. Glucose-6-phosphate dehydrogenase (G6PD)

Explanation:
G6PD deficiency is an X-linked disorder. Primaquine can trigger hemolytic anemia in such individuals.
Other listed enzymes do not cause red cell lysis since RBCs lack mitochondria.

4) Erythromycin-Induced Hearing Loss

Question:
A Russian youngster developed hearing loss after erythromycin treatment. The cause is:

A. Inhibition of mitochondrial protein synthesis
B. Inhibition of mitochondrial RNA synthesis
C. Inhibition of mitochondrial DNA replication
D. Weakening and tearing of the eardrum

✅ Correct Answer: A. Inhibition of mitochondrial protein synthesis

Explanation:
Certain antibiotics like erythromycin affect mitochondrial ribosomes due to their similarity to bacterial ribosomes, causing ototoxicity. The ear drum is not affected.

5) Enzyme Catalyzing High-Energy Phosphorylation in Glycolysis

Question:
Which enzyme catalyzes high-energy phosphorylation of substrates during glycolysis?

A. Pyruvate kinase
B. Phosphoglycerate kinase
C. Triose phosphate isomerase
D. Glyceraldehyde-3-phosphate dehydrogenase

✅ Correct Answer: D. Glyceraldehyde-3-phosphate dehydrogenase

Explanation:
This enzyme uses NAD⁺ to add inorganic phosphate to glyceraldehyde-3-phosphate, forming 1,3-bisphosphoglycerate.
Phosphoglycerate kinase and pyruvate kinase generate ATP, but do not perform oxidation reactions.

6) 47,XYY Karyotype Origin

Question:
A 13-year-old boy with behavioral issues and a 47,XYY karyotype likely inherited this due to nondisjunction during:

A. Meiosis I of paternal spermatogenesis
B. Meiosis I of maternal oogenesis
C. Meiosis II of paternal spermatogenesis
D. Meiosis II of maternal oogenesis

✅ Correct Answer: C. Meiosis II of paternal spermatogenesis

Explanation:
During paternal meiosis II, nondisjunction produces a 24,YY gamete, leading to a 47,XYY individual after fertilization.
Meiosis I nondisjunction would cause Klinefelter (47,XXY).

7) Diet Restriction in Cirrhosis with Hyperammonemia

Question:
In a cirrhotic patient with elevated blood ammonia, which nutrient should be most restricted?

A. Ethanol
B. Lipids
C. Proteins
D. Carbohydrates

✅ Correct Answer: C. Proteins

Explanation:
Proteins are the main source of nitrogen, which is converted to ammonia during catabolism. Restricting protein intake reduces ammonia production.

8) Glycolipid Receptor for Cholera Toxin

Question:
Which glycolipid acts as the receptor in the human intestine for cholera toxin?

A. GM1
B. GM3
C. Globoside
D. Cerebroside

✅ Correct Answer: A. GM1

9) Urea Cycle Disorder – Citrullinemia

Question:
A neonate presents with lethargy and seizures at 56 hours of life. Plasma ammonia is 887 μmol/L. Plasma amino acids show elevated citrulline but not argininosuccinate.
Which enzyme is deficient?

A. Arginase
B. Argininosuccinate lyase
C. Argininosuccinate synthetase
D. Carbamoyl phosphate synthetase I

✅ Correct Answer: C. Argininosuccinate synthetase

Explanation:
Deficiency of argininosuccinate synthetase blocks conversion of citrulline to argininosuccinate, causing type I citrullinemia.

10) Associated Disorder with Insulin Resistance

Question:
Considering the patient in the previous question, which disorder is also likely present?

A. Low blood pressure
B. Polycystic ovary syndrome (PCOS)
C. Fatty liver – Nonalcoholic steatohepatitis (NASH)
D. Hypouricemia

✅ Correct Answer: C. Fatty liver – Nonalcoholic steatohepatitis (NASH)

Explanation:
Insulin resistance is associated with type 2 diabetes, central obesity, hypertension, low HDL, high triglycerides, elevated uric acid, and NASH.
PCOS occurs only in women but is also part of the insulin resistance spectrum.

Clinical Biochemistry Prometric Exam MCQ 2025 has been developed by our professional team; Rapid Access Guide is the best seller book for all Gulf Countries Exams since 2000. It has an array of all topics; thousands of updated questions with correct answers and explanations certainly will help you to pass the exam at the very first attempt.

Job Application – General overview

There are many hospitals and Clinics in gulf Countries that have a Clinical Biochemistry specialty. You need to pass the Prometric exams to apply for a job in gulf countries. Generally, the minimum experience required is three years. You can visit the respective Health Authority websites to find the eligibility criteria. Once you have passed the exam, you can contact them for a job interview—some of them recruiting directly, and many of them taking interviews online.

The Prometric Application and Dataflow process is the most important factor while doing registration. Finishing it without any mistakes is very important, or it will lead to rejection of the application. Dataflow takes typically 30 to 45 days to issue the report. You can proceed with the exam booking if it is a positive report. If it is a negative dataflow report, you can still contact them for re-evaluation. If it is a genuine reason, they will verify your certificate again. Meanwhile, Rapid Access Guide Publishers are providing the Prometric Exam booking and Dataflow process on behalf of you.

The below documents are required for proceeding with the exam booking process.

• A recent photograph (passport size)
• Copy of your valid passport.
• Your educational qualification certificates.
• Your experience certificates.
• Practice license or registration (From your Home / Working country)
• The Good Standing Certificate (GSC)
• A medical fitness test in case the applicant is aged 65 and above.

This MCQ-based Reviewer book is beneficial for the following Prometric exams.

1. DHA(DOH) Exam – Dubai Health Authority. (Dubai Prometric)
2. MOH Exam– Ministry of Health, Sharjah, UAE. (Sharjah Prometric)
3. DHCC Exam – Dubai Healthcare city.
4. HAAD Exam– Health Authority of Abu Dhabi. (Pearson VUE Test)
5. NHRA Exam – National Health Regulatory Authority, Bahrain.
6. QCHP Exam – Qatar Council for Healthcare Practitioners. (Qatar Prometric)
7. SMLE Exam – Saudi Medical Licensing Exam. (Saudi Prometric)
8. OMSB Exam – Oman Medical Specialty Board. (Oman Prometric)
9. KMLE – Kuwait Medical Licensing Exam – Kuwait

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The Clinical Biochemistry book is a great resource for those preparing for the Prometric Exam. It covers all of the topics in the exam and includes practice questions and answer explanations. The book also contains helpful tips and strategies for taking the exam.

The Clinical Biochemistry book is a comprehensive study guide that covers all the topics tested on the Prometric exam. The book contains over 2,000 practice questions, mostly added clinical scenario and case base study questions as well as detailed explanations of the concepts behind each question. The book also includes plenty of practice exam, so you can get a feel for what the actual exam will be like. The Clinical Biochemistry book is an essential tool for anyone who is serious about passing the Prometric exam.